The Arizona Cardinals are placing rookie running back Jeremiyah Love on injured reserve with a high-ankle sprain, a move first reported by NFL Network's Ian Rapoport. Sources told NFL Network the injury will sideline Love for 4-5 weeks.

Love suffered the sprain in Week 8, and the IR designation guarantees he'll miss at least the next four games. It's a significant loss for Arizona: Love had established himself as one of the team's top offensive players as a rookie, and the Cardinals' offense will have to find production elsewhere while he recovers.

The fantasy football ripple effects are immediate. Tyler Allgeier is in line for a massive uptick in reps with Love shelved, per Yahoo Sports, making him the obvious waiver-wire priority for managers scrambling at running back. If the 4-5 week timeline holds, Love could return for the stretch run — but high-ankle sprains are notoriously unpredictable, and the Cardinals will have little incentive to rush their rookie back.