No. 11 Notre Dame will be shorthanded up front for the biggest game of its season. Defensive tackles Jason Onye and Francis Brewu, both listed as questionable with knee issues during the week, have been ruled out for Saturday night's home date with No. 1 Miami, per Yahoo Sports.

The absences sting at the worst possible time. The Irish host the top-ranked Hurricanes in South Bend with more than a marquee rivalry win on the line — Yahoo Sports notes Notre Dame has a chance to steal the top College Football Playoff seed with an upset. Losing two interior defensive linemen against a No. 1 team puts added pressure on the rest of the Irish front to hold up.

The matchup drew the full Week 10 spotlight, headlining ESPN's College GameDay, where celebrity guest picker Jason Sudeikis leaned into his personal ties and 'guaranteed' a Notre Dame upset. The betting markets were less romantic, with SportsLine's model among the outlets releasing picks on the 1-versus-11 showdown.

The Sporting News and others carried live scoring and highlights throughout the night as two of the sport's most recognizable programs — both CFP contenders — settled it on the field.