Friday's crossover slate has the prediction machines working overtime. CBS Sports' SportsLine model released its best bets for the Week 10 ACC matchup between the Virginia Tech Hokies and SMU Mustangs, headlining the night's college football action.

On the hardwood, the same model weighed in on Kentucky hosting James Madison in Friday night college basketball, offering picks for the Wildcats' early-season test against the Dukes.

The pick-making extends beyond Friday. Yahoo Sports writers published their Week 10 selections for every Big Ten game plus five national matchups, against the spread and straight up. The outlet's college fantasy analysts Eric Froton and Nick Bromberg also went bold with their Week 10 fantasy predictions.

With conference races tightening and basketball season barely underway, the weekend offers a rare stretch where football and hoops handicapping share the marquee — and the models and writers don't always agree.